As it was the sixth herpesvirus isolated it was then subsequently renamed human herpesvirus 6. HHV-6A and HHV-6B are double-stranded DNA viruses within the Betaherpesvirinae subfamily and of. Pdf Human Herpesvirus 6 And Malignancy A Review Most children have been infected by age three. . Causes Kaposis sarcoma E. Humanherpesvirus 6 HHV-6 is a recently discovered virus that onthe basis ofserologi-cal evidence seems to infect mostchildren by the age of three years However the clinical manifestations of primary HHV-6 infection and reactivation have not been well defined except for the report byYamanishi et al2 that identified HHV-6 as the agent of exanthem. Human herpes virus 6 as has human herpes virus 7 but to a lesser extent has been associated with exanthem subitum or roseola. Appears as a mononucleosis-like illness in adults. Human herpesvirus 6 HHV-6 has the following characteristics except A. Human herpesvirus 6 HHV-6